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Clostridium and Your Cat's Constipation

Constipation is an ongoing problem in cats, which has become a dominant force for causing inflammatory conditions in their digestive system. Many theories exist for underlying causes. Ideas ranging from an inability to process grains and allergies to certain proteins exist in attempt to target an underlying problem. Many of these theories have been shown in studies not to have any bearing on constipation, and the veterinary community is left with more questions than answers. What we do know is that constipation is prevalent in the feline species (including our housecats larger cousins like the lion!), so we can safely debunk a popular trend of feeding raw food to eliminate intestinal disorders, which cause more problems than they fix.

Constipation and imbalances in gut bacteria, including Clostridium species, can be related. Clostridium is the most common bacteria we find associated with constipation, which we can determine by evaluating your cat’s feces with a molecular test called a Fecal PCR. Here's how constipation contributes to imbalances in gut bacteria, including Clostridium:

1. Altered Gut Transit Time: Constipation can result in a prolonged transit time in the gut. When stool remains in the colon for extended periods, it provides an environment conducive to the overgrowth of certain bacterial species, including Clostridium. These bacteria may multiply and dominate the gut environment.

2. Reduced Peristalsis: Peristalsis is the rhythmic contraction and relaxation of the muscles in the digestive tract that helps move food and waste through the intestines. In constipation, peristalsis may be reduced, leading to stagnation of contents in the colon. This stagnant environment can favor the growth of specific bacteria, potentially including Clostridium.

3. Changes in Gut Microbiota Composition: Chronic constipation can cause alterations in the composition of gut microbiota. The microbiota in constipated individuals may differ from those in individuals with regular bowel movements. This altered microbiota composition may include an overgrowth of certain bacterial species, potentially including Clostridium.

4. Impaired Mucus and Barrier Function: Constipation can damage the mucus layer and the gut barrier, making the intestinal lining more susceptible to bacterial overgrowth. Clostridium species may take advantage of this compromised barrier function and proliferate.

5. Diet and Nutritional Factors: Constipation is often associated with a diet low in fiber and inadequate hydration. A diet low in fiber can influence the gut microbiota composition and reduce the production of short-chain fatty acids (SCFAs), which are essential for gut health and maintaining a balanced microbiota.

6. Toxin Production by Clostridium: Some Clostridium species can produce toxins that affect gut motility and may contribute to constipation or exacerbate it. These toxins can interfere with the normal functions of the digestive system, potentially leading to a vicious cycle of constipation and further bacterial imbalances.

Improving constipation in a cat involves a combination of dietary changes, increased water intake, litter box management, and regular exercise. Here are some recommendations to help alleviate constipation in your cat:

Dietary Changes:

  • Increase Fiber: Offer your cat a high-fiber diet, which can help promote regular bowel movements. Consider switching to a cat food formulated for digestive health or high-fiber cat food.

  • Wet Food: Include wet canned food in your cat's diet. Wet food contains more moisture and can aid in hydration, which is important for softening the stool.


  • Ensure your cat has access to fresh, clean water at all times. Cats are more likely to drink water when it's fresh and appealing to them.

  • Consider using a cat water fountain, which may encourage your cat to drink more water.

Litter Box Management:

  • Keep the litter box clean and odor-free to encourage your cat to use it regularly.

  • Ensure the litter box is easily accessible and in a quiet, low-traffic area where your cat feels comfortable.

Regular Exercise:

  • Encourage physical activity and playtime to keep your cat active and maintain a healthy digestive system. Exercise helps promote bowel movements.

  • Use interactive toys or engage in interactive play sessions with your cat to encourage movement.

Enrichment and Mental Stimulation:

  • Provide mental stimulation through puzzle feeders and interactive toys to reduce stress and anxiety, which can contribute to constipation.

  • Offer scratching posts and climbing trees to encourage natural behaviors and movement.

Regular Vet Check-ups:

  • Schedule regular check-ups with your veterinarian to monitor your cat's overall health and discuss any concerns about constipation.

  • Follow your veterinarian's advice on managing constipation and any potential underlying medical conditions.

Supplements or Medications:

  • Your veterinarian may recommend specific supplements or medications to help manage constipation. These could include laxatives, stool softeners, or probiotics.

  • Never administer any medication to your cat without consulting a veterinarian first.


  • Regular grooming, especially for long-haired cats, can prevent hairballs and decrease the likelihood of constipation caused by ingesting excessive fur.

If your cat's constipation persists or worsens despite these measures, or if you notice any signs of distress, loss of appetite, or significant changes in behavior, consult your veterinarian promptly for a thorough evaluation and appropriate treatment.

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